7,8-DHF 25mg/ml/20ml and 28 similar items

7,8-DHF (7,8-Dihydroxyflavone)- is a naturally occurring flavonoid with cognition-enhancing properties. Its recent discovery has spurred research into its unique properties, it is able to cross the blood brain barrier effectively. 7,8-DHF is believed to directly bind the tropomyosin-related kinase B (TrkB) receptor, which is the endogenous receptor for BDNF (Brain Derived Neurotrophic Factor). BDNF can be thought of as ?MiracleGro for the brain;? it is one of the main neurotrophic factors responsible for neurogenesis and increases dendritic outgrowth and density. By enhancing TrkB expression, it may be possible to increase the rate new synapses are formed, thus enhancing learning. Some researchers hypothesize that 7,8-DHF does not bind TrkB directly, but instead acts on an unknown pathway that results in the same end result--increased TrkB activity. 7,8-DHF is believed to have a similar degree of neurogenic activities as BDNF. On top of its effects on neurogenesis, 7,8-DHF is also neuroprotective. It has antioxidant properties in the brain that are independent of its TrkB activity. While these mechanisms are not fully understood, it is believed to activate the Akt/PKB pathway.